Methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-propenoate
[CAS# 117428-51-0]

Identification

• Name: Methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-propenoate
• Molecular Formula: C₁₂H₁₃ClO₃
• Molecular Weight: 240.68
• CAS Registry Number: 117428-51-0
• EC Number: 473-070-7
• SMILES: CO/C=C(C1=CC=CC=C1CCl)/C(=O)OC

Properties

• Density: 1.2±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.532, Calc.^*
• Boiling Point: 373.4±42.0 °C (760 mmHg), Calc.^*
• Flash Point: 155.0±26.9 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS05 Danger
• Risk Statements: H290-H314
• Safety Statements: P234-P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P363-P390-P405-P406-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Skin sensitization	Skin Sens.	1	H317

Discovery and Applications

Methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-acrylate is a noteworthy compound that has attracted much attention due to its unique structure and wide range of applications. As part of advanced organic chemistry research, this compound has a unique (E)-configured double bond and functional groups, including a methoxy group and a chloromethylphenyl group. These properties contribute to its reactivity and usefulness in various fields.

The synthesis of methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-acrylate stems from efforts to develop functionalized acrylates with enhanced reactivity and application potential. The (E) configuration of the double bond plays a key role in its chemical behavior, affecting how the compound interacts in various reactions. The methoxy group enhances its nucleophilicity, while the chloromethylphenyl group enhances its electrophilicity, making the compound versatile in chemical transformations.

In the pharmaceutical industry, this compound is an important intermediate in the synthesis of more complex molecules. It is able to participate in a range of chemical reactions and can therefore be used to develop new drugs. Methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-propenoate plays an important role in drug discovery and development by promoting the production of biologically active compounds.

In addition, the compound can be used in materials science for the production of specialty polymers and resins. Its chemical properties can help develop materials with specific properties, such as enhanced durability or unique optical characteristics. This makes it valuable in creating advanced materials for industrial applications, including specialty coatings and polymer formulations.

References

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