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2-Phosphonobutane-1,2,4-tricarboxylic acid
[CAS# 37971-36-1]

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Identification
ClassificationOrganic raw materials >> Organic phosphine compound
Name2-Phosphonobutane-1,2,4-tricarboxylic acid
SynonymsPBTC; PBTCA
Molecular StructureCAS # 37971-36-1, 2-Phosphonobutane-1,2,4-tricarboxylic acid
Molecular FormulaC7H11O9P
Molecular Weight270.13
CAS Registry Number37971-36-1
EC Number253-733-5
SMILESC(CC(CC(=O)O)(C(=O)O)P(=O)(O)O)C(=O)O
Properties
Density1.25 (50% aq.)
Safety Data
Hazard Symbolssymbol symbol   GHS05;GHS07 Danger  Details
Risk StatementsH290-H314-H319  Details
Safety StatementsP234-P260-P264-P264+P265-P280-P301+P330+P331-P302+P361+P354-P304+P340-P305+P351+P338-P305+P354+P338-P316-P321-P337+P317-P363-P390-P405-P406-P501  Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Eye irritationEye Irrit.2H319
Substances or mixtures corrosive to metalsMet. Corr.1H290
Skin corrosionSkin Corr.1BH314
Serious eye damageEye Dam.1H318
Skin corrosionSkin Corr.1AH314
Specific target organ toxicity - repeated exposureSTOT RE2H373
Skin irritationSkin Irrit.2H315
Specific target organ toxicity - single exposureSTOT SE3H371
Transport InformationUN 3265
SDSAvailable
up Discovery and Applications
2-Phosphonobutane-1,2,4-tricarboxylic acid (PBTC) was developed in the late 20th century as demand for effective water treatment solutions grew to combat scale and corrosion in industrial systems. Researchers sought a compound that could effectively inhibit scale formation and remain stable under harsh conditions. PBTC is a colorless to pale yellow liquid or crystalline solid that is highly soluble in water. It combines three carboxyl groups with one phosphonic acid group, giving it a strong metal chelating ability. This structure enables PBTC to chelate metal ions such as calcium, magnesium, and iron, preventing them from precipitating and minimizing scale formation. This development marked a major advancement in scale inhibition technology.

PBTC is primarily used in industrial water treatment systems. Its ability to chelate metal ions makes it effective in preventing scale formation in cooling towers, boilers, and heat exchangers. It also provides corrosion protection by forming a protective film on metal surfaces, thereby reducing equipment maintenance costs. PBTC is used in reverse osmosis systems to prevent membrane fouling and scaling. Its compatibility with membrane materials and high efficiency in chelating metal ions make it a preferred scale inhibitor in desalination and water purification processes.

PBTC can be used in detergent formulations due to its ability to improve cleaning performance. By chelating metal ions in hard water, they are prevented from interfering with surfactants, thereby increasing the effectiveness of detergents and reducing detergent usage. PBTC is also used in industrial cleaning applications to prevent scale buildup on equipment and improve the efficiency of the cleaning process. It helps maintain optimal operating conditions and extend the life of machinery.

In the oil and gas industry, PBTC is used to control scale formation in drilling and production operations. It helps prevent scale buildup in pipelines, wells, and processing equipment, ensuring uninterrupted production and reducing the risk of operational disruptions. The corrosion inhibition properties of PBTC can be used to protect metal surfaces in various oil and gas infrastructures, contributing to the integrity and life of equipment.

PBTC is used in the pulp and paper industry to control scaling in pulp digesters, bleaching systems, and paper machines. Its chelating properties help maintain system cleanliness and improve the efficiency of the production process. It is also used as a processing aid to improve the stability and quality of paper products by preventing metal ion contamination and improving the brightness and texture of the final product.

PBTC is used as a stabilizer in micronutrient solutions and fertilizers in agricultural applications. Its chelation action ensures that essential nutrients are available to plants, improving absorption and effectiveness while preventing nutrient retention in the soil.

PBTC has superior scale inhibition and metal ion sequestration capabilities compared to traditional agents, providing reliable performance in a variety of industrial applications. Its chemical stability at high temperatures and pH changes makes it suitable for use in a variety of demanding environments. PBTC is biodegradable and has low toxicity, making it an environmentally friendly choice for water treatment and other applications.

PBTC is generally considered safe for its intended use, it is non-toxic and biodegradable, reducing environmental impact. However, handling guidelines recommend the use of protective equipment to avoid skin and eye contact, as PBTC may be mildly irritating.

References

2024. Research Status of Copper Film Slurries for Through-Silicon Via Process. Journal of Electronic Materials, 53(12).
DOI: 10.1007/s11664-024-11629-1
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